TMG Supplement 1000mg Methylation & Longevity Support

The methyl donor your longevity stack has been missing.

TMG (trimethylglycine, also called betaine anhydrous) is a naturally occurring compound your body uses in a process called methylation — a chemical reaction that happens billions of times per day and affects everything from DNA repair to detoxification to how well you process NAD+ supplements.

As you age (and as you supplement things like NAD+), your body burns through methyl groups fast. Low methylation is linked to elevated homocysteine, sluggish energy, and reduced effectiveness of longevity supplementation.

Hazel's Choice TMG Supplement delivers 1,000mg of pure trimethylglycine per serving — a clean, honest formulation designed to pair perfectly with your NAD+ routine or stand on its own for methylation support.

Why methylation matters

●       Supports healthy homocysteine levels — TMG helps convert homocysteine back into methionine, an important amino acid

●       Fuels the methylation cycle — required for DNA repair, neurotransmitter synthesis, and cellular signaling

●       Pairs with NAD+ supplementation — NAD+ metabolism requires methyl groups, and TMG supplies them

●       Supports liver health — TMG (betaine) is used clinically for liver support

●       May support workout output — as betaine anhydrous, it has research behind strength and power

Who this is for

●       Anyone taking NAD+, NMN, or NR — TMG is the pairing your body needs

●       People concerned about elevated homocysteine or MTHFR gene variants

●       Adults over 30 wanting stronger methylation and metabolic support

●       Athletes using betaine for training support

●       Anyone building a comprehensive longevity supplement routine

What's inside — and what's not

In every 2-capsule serving:

●       1,000 mg TMG (Trimethylglycine / Betaine Anhydrous)

●       Vegetable capsule shell

What's not:

No fillers, artificial flavors, colors, preservatives, dairy, soy, gluten, or GMO ingredients.

How to take it

Take 2 capsules per day with food. If pairing with NAD+ or NMN, take TMG at the same time.

For higher-dose protocols under practitioner guidance, dosing can be adjusted. Do not exceed 6 capsules per day without professional supervision.

Quality you can verify

●       1,000 mg per serving — an effective, research-aligned dose

●       Made in GMP-certified facilities

●       Third-party tested for purity

●       Non-GMO, gluten-free, no unnecessary additives

●       180 capsules per bottle — a 90-day supply at 2 capsules per day

Frequently Asked Questions

What is TMG used for?

TMG (trimethylglycine) supplies methyl groups the body uses in methylation — a chemical reaction critical for DNA repair, homocysteine metabolism, liver function, and processing supplements like NAD+, NMN, and NR.

Do I need TMG with NAD+?

Many longevity practitioners recommend it. When you supplement NAD+ precursors, your body uses extra methyl groups to metabolize them. TMG replenishes those methyl groups, supporting the full pathway.

TMG vs betaine — are they the same?

Yes. TMG (trimethylglycine) and betaine anhydrous are the same molecule. Some brands market it as betaine for athletic performance, others as TMG for methylation and longevity — same compound, different framing.

How much TMG should I take daily?

The standard supplemental dose is 500–2,000 mg per day. Our 2-capsule serving delivers 1,000 mg — right in the middle of the research range. Higher doses are used clinically under supervision.

Does TMG help with MTHFR gene variants?

TMG provides an alternate pathway for methylation that doesn't depend on the MTHFR enzyme, which is why many people with MTHFR variants find it a helpful part of their routine. Work with a knowledgeable practitioner for personalized guidance.

When is the best time to take TMG?

With food. If pairing with NAD+ or NMN, take them at the same time.

Are there any side effects?

TMG is generally well tolerated. At very high doses (well above 3,000 mg), some people report mild digestive upset or a fishy body odor from trimethylamine production. Sticking to typical doses avoids this.